The invention of the tomacco plant — Season 11, Episode 5
In 1999, Homer uses nuclear energy to create a hybrid of tomato and tobacco plants: the "tomacco."
This inspired US "Simpsons" fan Rob Baur to create his own plant. In 2003, Baur grafted together a tobacco root and a tomato stem to make "tomacco." Writers for "The Simpsons" were so impressed that they invited Baur and his family to their offices and ate the tomacco fruit themselves.